|Series||Immunological reviews -- no. 118|
This book details specific animal models for a variety of autoimmune disorders. The contributors are recognized authorities who deal with the panoply of experimentally induced autoimmune disorders, including encephalomyelitis, allergic neuritis, uveoretinitis, myocarditis, and : $ The Autoimmune Diseases. Book • Fifth Edition • In this review we describe both human diseases and the experimental models of autoimmune orchitis and oophoritis, highlighting many aspects, including the relevant role of lymph node-specific regulatory T cells . The focus of this chapter is to explore the link between autoimmune mechanisms underlying COP and IPF as models for autoimmune disorders of the lung. To do so, we discuss the history and the clinical features of COP and IPF, followed by a summary of the autoimmune, genetic, environmental features, current concepts of pathogenesis, and the therapies currently available and under investigation for . Autoimmune disease models. San Diego: Academic Press, © (OCoLC) Online version: Autoimmune disease models. San Diego: Academic Press, © (OCoLC) Material Type: Internet resource: Document Type: Book, Internet Resource: All Authors / .
This textbook, edited by Robert Lahita MD of Lupus textbook fame is a different approach to autoimmune diseases. The first part of the book offers an overview of the main aspects of immune response in basic science, while part 2 deals with the clinical aspects of that he dedicates 12 chapters to approaching the autoimmune diseases by the organ that they act s: 4. Description. Since publication of the 4th Edition of The Autoimmune Diseases in , the understanding of the immune mechanisms underlying autoimmunity and autoimmune disease has significantly deepened and broadened. This fully revised 5th Edition incorporates new material and combines common themes underlying inductive and effector mechanisms and therapies that relate generally to the autoimmune Edition: 5. Current Protocols in Immunology is a comprehensive source for protocols and overviews in the field of immunology including, in vivo and in vitro assays to study lymphocyte cells, the isolation and differentiation of stem and progenitor cells, flow cytometry and cell sorting, and animal models of infections disease. Genetic factors such as HLA type are important in autoimmune disease, and it is probable that each disease involves several factors. Autoimmune mechanisms are pathogenic in experimental and spontaneous animal models associated with the development of autoimmunity. Human autoantibodies can be directly pathogenic.
The Mosaic of Autoimmunity: The Novel Factors of Autoimmune Diseases describes the multifactorial origin and diversity of expression of autoimmune diseases in humans. The term implies that different combinations of factors in autoimmunity produce varying and unique clinical pictures in a wide spectrum of autoimmune diseases. Dr. Rose’s original investigations on the autoimmune basis of thyroid disease in opened the present era of research on autoimmunity. He has since investigated many areas of autoimmunity and related issues in clinical and basic immunology. Dr. Rose is the author or co-author of over scientific papers and editor or co-editor of 24 books. Autoimmunity-which affects up to 10% of the world's population-can damage nearly every tissue or cell type of the human body with greatly debilitating or fatal results. In Autoimmunity: Methods and Protocols, expert medical researchers describe in step-by-step detail molecular techniques and in vitro/in vivo model systems for discovering the. The second edition of Autoimmunity: Methods and Protocols researchers in the field detail many of the most up-to-date methods which are now commonly used to study autoimmunity. The first half the book focuses on methods and protocols used to assess immunological and biochemical pathways of diseases pathogenesis in human subjects.